GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota

GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota

Objectives: Gut microbiota increases energy availability through fermentation of dietary fibers to short-chain fatty acids in conventionally raised mice. Energy deficiency in germ-free (GF) mice increases glucagon-like peptide-1 (GLP-1) levels, which slows intestinal transit. To further analyze the...

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Main Authors: Thomas U. Greiner (Author), Ara Koh (Author), Eduard Peris (Author), Mattias Bergentall (Author), Malin E.V. Johansson (Author), Gunnar C. Hansson (Author), Daniel J. Drucker (Author), Fredrik Bäckhed (Author)
Format: Book
Published: Elsevier, 2024-05-01T00:00:00Z.
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