Pharmacokinetics, tissue distribution, and plasma protein binding rate of curcumol in rats using liquid chromatography tandem mass spectrometry

• Main Authors: Zhaoxu Yang (Author), Qingmei Sun (Author), Sheng Wang (Author), Bingbing Tang (Author), Chenxing Yuan (Author), Yue Wu (Author), Jiabin Dai (Author), Chen Yang (Author), Lingkun Wang (Author), Qian Zhou (Author), Jincheng Wang (Author), Qinjie Weng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Curcumol is one of the major active ingredients isolated from the traditional Chinese medicine Curcumae Rhizoma and is reported to exhibit various bioactivities, such as anti-tumor and anti-liver fibrosis effects. However, studies of curcumol pharmacokinetics and tissue distribution are c...