Targeting glutathione S-transferase M4 in Ewing sarcoma

• Main Authors: Rupeng eZhuo (Author), kenneth ekosak (Author), savita esankar (Author), Elizabeth T Wiles (Author), Ying eSun (Author), Jianxing eZhang (Author), Janet eAyello (Author), Glenn ePrestwich (Author), Paul eShami (Author), Mitchell S Cairo (Author), Stephen eLessnick (Author), Wen eLuo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ewing sarcoma is a malignant pediatric bone and soft tissue tumor. Although the 5-year survival rate of localized disease approaches 75%, the prognosis of metastatic and/or therapy-resistant disease remains dismal despite the wide use of aggressive therapeutic strategies. We previously reported that...