Disruption of Nrf2 Enhances Upregulation of Nuclear Factor-κB Activity, Proinflammatory Cytokines, and Intercellular Adhesion Molecule-1 in the Brain after Traumatic Brain Injury

• Hoofdauteurs: Wei Jin (Auteur), Handong Wang (Auteur), Wei Yan (Auteur), Lizhi Xu (Auteur), Xiaoliang Wang (Auteur), Xiaoning Zhao (Auteur), Xiaohe Yang (Auteur), Gang Chen (Auteur), Yan Ji (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2008-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Inflammatory response plays an important role in the pathogenesis of secondary brain injury after traumatic brain injury (TBI). Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that plays a crucial role in cytoprotection against inflammation. The present study investi...