Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors

• Главные авторы: Martial Caillaud (Автор), Danielle Thompson (Автор), Wisam Toma (Автор), Alyssa White (Автор), Jared Mann (Автор), Jane L. Roberts (Автор), John W. Bigbee (Автор), David A. Gewirtz (Автор), M. Imad Damaj (Автор)
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• Опубликовано: MDPI AG, 2022-06-01T00:00:00Z.
• Предметы: article
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Paclitaxel is widely used in the treatment of various types of solid malignancies. Paclitaxel-induced peripheral neuropathy (PIPN) is often characterized by burning pain, cold, and mechanical allodynia in patients. Currently, specific pharmacological treatments against PIPN are lacking. Curcumin, a...