Downregulation of histone deacetylase 8 (HDAC8) alleviated the progression of oral submucous fibrosis

• Main Authors: Hui-Wen Yang (Author), Yi-Hwa Sun (Author), Chih-Yuan Fang (Author), Yoichi Ohiro (Author), Heng-Yi Liao (Author), Yi-Wen Liao (Author), Yu-Hsun Kao (Author), Cheng-Chia Yu (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oral submucous fibrosis (OSF) is a premalignant disorder that is associated with betel nut chewing. The purpose of the study was to establish the role of histone deacetylase (HDAC) 8, one of histone deacetylases, in the regulation of fibrotic conditions to provide a therapeutic p...