Demethylcalabaxanthone from <i>Garcinia mangostana</i> Exerts Antioxidant Effects through the Activation of the Nrf2 Pathway as Assessed via Molecular Docking and Biological Evaluation

• Main Authors: Simona De Vita (Author), Milena Masullo (Author), Sabrina Grambone (Author), Paloma Bermejo Bescós (Author), Sonia Piacente (Author), Giuseppe Bifulco (Author)
• Format: Bog
• Udgivet: MDPI AG, 2023-11-01T00:00:00Z.
• Fag: article
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Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway activation promotes the expression of antioxidant enzymes in response to rising oxidative stress, resulting in reactive oxygen species (ROS) detoxification and playing a central role in the maintenance of intracellular redox homeostasis and...