Evaluation of the inhibition performance of pyrrole derivatives against CYP450 isoforms
Cytochrome P450 is a heme-containing superfamily accountable for the oxidation of various pharmacologically active drugs. The aim of this study was to conduct in silico and in vitro activity assessments of recently synthesized pyrrole-based compounds against three major CYP450 isoforms - CYP1A2, CYP...
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Pensoft Publishers,
2024-05-01T00:00:00Z.
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