Capsaicin Is a Negative Allosteric Modulator of the 5-HT3 Receptor

In this study, effects of capsaicin, an active ingredient of the capsicum plant, were investigated on human 5-hydroxytryptamine type 3 (5-HT3) receptors. Capsaicin reversibly inhibited serotonin (5-HT)-induced currents recorded by two-electrode voltage clamp method in Xenopus oocytes. The inhibition...

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Main Authors: Eslam El Nebrisi (Author), Tatiana Prytkova (Author), Dietrich Ernst Lorke (Author), Luke Howarth (Author), Asma Hassan Alzaabi (Author), Keun-Hang Susan Yang (Author), Frank C. Howarth (Author), Murat Oz (Author)
Format: Book
Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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