Exploration of the influence of KHDC3L gene knock-out by CRISPR/Cas9 technology on PEG3 promoter

• Main Authors: Arezoo Jokar (Author), Shayan Khalili Alashti (Author), Maryam Baneshi (Author), Ali Rastegarian (Author), Kimia Sadat Hashemi (Author), Mohadese Koohi Aliabadi (Author), Mojtaba Kashfi (Author), amir savardashtaki (Author)
• Format: Book
• Published: Shiraz University of Medical Sciences, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aim: CRISPR-Cas9, enable precise DNA manipulation via RNA-guided breaks. KHDC3L and PEG3 genes are vital; CRISPR-Cas9 studies their roles in reproduction, development, and gene regulation. Focusing on KHDC3L's impact on PEG3 promoter in HCT116 cells, insights into gene functions...