New Oxazolidinones for Tuberculosis: Are Novel Treatments on the Horizon?

• Main Authors: Ricky Hao Chen (Author), Andrew Burke (Author), Jin-Gun Cho (Author), Jan-Willem Alffenaar (Author), Lina Davies Forsman (Author)
• 格式: 图书
• 出版: MDPI AG, 2024-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity. As such, it is imperative to identify novel alterna...