Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms

• Main Authors: Vincent Kam Wai Wong (Author), Wu Zeng (Author), Juan Chen (Author), Xiao Jun Yao (Author), Elaine Lai Han Leung (Author), Qian Qian Wang (Author), Pauline Chiu (Author), Ben C. B. Ko (Author), Betty Yuen Kwan Law (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal herbs as potential anti-tumor agents through autophagic induction, which finally lead to autophagy mediated-cell death in apoptosis-resistant ca...