Characterization and In Vivo Antiangiogenic Activity Evaluation of Morin-Based Cyclodextrin Inclusion Complexes

• Main Authors: Federica De Gaetano (Author), Fatima Margani (Author), Vincenzina Barbera (Author), Valeria D'Angelo (Author), Maria Paola Germanò (Author), Venerando Pistarà (Author), Cinzia Anna Ventura (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Morin (MRN) is a natural compound with antiangiogenic, antioxidant, anti-inflammatory, and anticancer activity. However, it shows a very low water solubility (28 μg/mL) that reduces its oral absorption, making bioavailability low and unpredictable. To improve MRN solubility and positively affect its...