A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties

• Main Authors: Abed El-Ha (Author), Jamilah Abusarah (Author), Yun Emma Cui (Author), Nehme El-Hachem (Author), Ian Hammond-Martel (Author), Hugo Wurtele (Author), Sini Thomas (Author), Maryam Ahmadi (Author), Mohammad Balood (Author), Sébastien Talbot (Author), Moutih Rafei (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phenotypic screening is an ideal strategy for the discovery of novel bioactive molecules. Using a customized high-throughput screening (HTS) assay employing primary T lymphocytes, we screened a small library of 4,398 compounds with unknown biological function/target to identify compounds eliciting i...