Identification and Heterologous Expression of the Biosynthetic Gene Cluster Encoding the Lasso Peptide Humidimycin, a Caspofungin Activity Potentiator

• Principais autores: Marina Sánchez-Hidalgo (Autor), Jesús Martín (Autor), Olga Genilloud (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Humidimycin (MDN-0010) is a ribosomally synthesized and post-translationally modified peptide (RiPP) belonging to class I lasso peptides, and is structurally related to siamycins, which have been shown to have strong antimicrobial activities against Gram-positive bacteria and to possess anti-HIV act...