Identification and Heterologous Expression of the Biosynthetic Gene Cluster Encoding the Lasso Peptide Humidimycin, a Caspofungin Activity Potentiator

Humidimycin (MDN-0010) is a ribosomally synthesized and post-translationally modified peptide (RiPP) belonging to class I lasso peptides, and is structurally related to siamycins, which have been shown to have strong antimicrobial activities against Gram-positive bacteria and to possess anti-HIV act...

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Principais autores: Marina Sánchez-Hidalgo (Autor), Jesús Martín (Autor), Olga Genilloud (Autor)
Formato: Livro
Publicado em: MDPI AG, 2020-02-01T00:00:00Z.
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