Identification and Heterologous Expression of the Biosynthetic Gene Cluster Encoding the Lasso Peptide Humidimycin, a Caspofungin Activity Potentiator

• Main Authors: Marina Sánchez-Hidalgo (Author), Jesús Martín (Author), Olga Genilloud (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2020-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Humidimycin (MDN-0010) is a ribosomally synthesized and post-translationally modified peptide (RiPP) belonging to class I lasso peptides, and is structurally related to siamycins, which have been shown to have strong antimicrobial activities against Gram-positive bacteria and to possess anti-HIV act...