Use of Capsaicin to Treat Pain: Mechanistic and Therapeutic Considerations

• Main Authors: Man-Kyo Chung (Author), James N. Campbell (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2016-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment of neuropathic pain. The analgesia lasts for several months after a single treatment. Capsaicin selectively activates TRPV1, a Ca2+-permeable cationic ion channel that is enriched in the terminals of certain...