Identification of Effective Anticancer G-Quadruplex-Targeting Chemotypes through the Exploration of a High Diversity Library of Natural Compounds

• Päätekijät: Chiara Platella (Tekijä), Francesca Ghirga (Tekijä), Pasquale Zizza (Tekijä), Luca Pompili (Tekijä), Simona Marzano (Tekijä), Bruno Pagano (Tekijä), Deborah Quaglio (Tekijä), Valeria Vergine (Tekijä), Silvia Cammarone (Tekijä), Bruno Botta (Tekijä), Annamaria Biroccio (Tekijä), Mattia Mori (Tekijä), Daniela Montesarchio (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2021-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

In the quest for selective G-quadruplex (G4)-targeting chemotypes, natural compounds have been thus far poorly explored, though representing appealing candidates due to the high structural diversity of their scaffolds. In this regard, a unique high diversity in-house library composed of ca. one thou...