G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth

• Main Authors: Whitney K. Petrie (Author), Megan K. Dennis (Author), Chelin Hu (Author), Donghai Dai (Author), Jeffrey B. Arterburn (Author), Harriet O. Smith (Author), Helen J. Hathaway (Author), Eric R. Prossnitz (Author)
• פורמט: ספר
• יצא לאור: Hindawi Limited, 2013-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Endometrial carcinoma is the most common cancer of the female reproductive tract. GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has been identified as the third estrogen receptor, in addition to ERα and ERβ. High GPER expression is predictive of poor survival in endometria...