Non-Invasive Low Pulsed Electrical Fields for Inducing BBB Disruption in Mice-Feasibility Demonstration

• Main Authors: Shirley Sharabi (Author), David Last (Author), Dianne Daniels (Author), Ido Didi Fabian (Author), Dana Atrakchi (Author), Yael Bresler (Author), Sigal Liraz-Zaltsman (Author), Itzik Cooper (Author), Yael Mardor (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood-brain barrier (BBB) is a major hurdle for the treatment of central nervous system disorders, limiting passage of both small and large therapeutic agents from the blood stream into the brain. Thus, means for inducing BBB disruption (BBBd) are urgently needed. Here, we studied the applicatio...