Novel ⁶⁸Ga-Labeled Pyridine-Based Fibroblast Activation Protein-Targeted Tracers with High Tumor-to-Background Contrast

• Main Authors: Arsyangela Verena (Author), Hsiou-Ting Kuo (Author), Helen Merkens (Author), Jutta Zeisler (Author), Shreya Bendre (Author), Antonio A. W. L. Wong (Author), François Bénard (Author), Kuo-Shyan Lin (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Compared to quinoline-based fibroblast activation protein (FAP)-targeted radiotracers, pyridine-based FAP-targeted tracers are expected to have faster pharmacokinetics due to their smaller molecular size and higher hydrophilicity, which we hypothesize would improve the tumor-to-background image cont...