Optical substrates for drug-metabolizing enzymes: Recent advances and future perspectives

• Main Authors: Qiang Jin (Author), JingJing Wu (Author), Yue Wu (Author), Hongxin Li (Author), Moshe Finel (Author), Dandan Wang (Author), Guangbo Ge (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-metabolizing enzymes (DMEs), a diverse group of enzymes responsible for the metabolic elimination of drugs and other xenobiotics, have been recognized as the critical determinants to drug safety and efficacy. Deciphering and understanding the key roles of individual DMEs in drug metabolism and...