Advances in nanoscale carrier-based approaches to reduce toxicity and enhance efficacy of podophyllotoxin

• Main Authors: Chaozheng Zhang (Author), Yi Zuo (Author), Tingting Zhang (Author), Xin Zhang (Author), Jie Ling (Author), Changqun Liu (Author), Hongyu Chen (Author), Xin Zhou (Author), Maolin Wang (Author), Yun Deng (Author), Yilan Liu (Author), Jun Lu (Author)
• Format: Book
• Published: Compuscript Ltd, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Podophyllotoxin (PPT), an aryltetralin-type lignan isolated from Podophyllum species, exhibits a wide range of biologic and pharmacologic activities, and mainly serves as an antiviral agent or antitumor drug in clinical applications. However, the therapeutic potential of PPT has been hindered due to...