Consequences of the Lack of CD73 and Prostatic Acid Phosphatase in the Lymphoid Organs

• Main Authors: Gennady G. Yegutkin (Author), Kaisa Auvinen (Author), Marika Karikoski (Author), Pia Rantakari (Author), Heidi Gerke (Author), Kati Elima (Author), Mikael Maksimow (Author), Ileana B. Quintero (Author), Pirkko Vihko (Author), Marko Salmi (Author), Sirpa Jalkanen (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD73, ecto-5'-nucleotidase, is the key enzyme catalyzing the conversion of extracellular AMP to adenosine that controls vascular permeability and immunosuppression. Also prostatic acid phosphatase (PAP) possesses ecto-5'-nucleotidase/AMPase activity and is present in leukocytes. However, i...