Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF‐β-Smad2/3 signaling and Wnt signaling in Neovascular Age‐Related Macular Degeneration

• Main Authors: Qian Chen (Author), Nan Jiang (Author), Yuhan Zhang (Author), Sihao Ye (Author), Xu Liang (Author), Xin Wang (Author), Xiang Lin (Author), Rongrong Zong (Author), Haoyu Chen (Author), Zuguo Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Subretinal fibrosis is a common pathological change that causes vision loss in neovascular age-related macular degeneration (nAMD). Treatment modalities for subretinal fibrosis are limited. In the present study, the effects of fenofibrate, a specific peroxisome proliferator-activated receptor alpha...