The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation

• Main Authors: Dennis Y. Kim (Author), Joanna Yu (Author), Ryan K. Mui (Author), Rieko Niibori (Author), Hamza Bin Taufique (Author), Rukhsana Aslam (Author), John W. Semple (Author), Sabine P. Cordes (Author)
• Format: Book
• Published: The Company of Biologists, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe appetite and weight loss define the eating disorder anorexia nervosa, and can also accompany the progression of some neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS). Although acute loss of hypothalamic neurons that produce appetite-stimulating neuropeptide Y (Npy) and...