Molecular analysis of iduronate -2- sulfatase gene in Tunisian patients with mucopolysaccharidosis type II

• Main Authors: Chkioua Latifa (Author), Khedhiri Souhir (Author), Ferchichi Salima (Author), Tcheng Rémy (Author), Chahed Henda (Author), Froissart Roseline (Author), Vianey-Saban Christine (Author), Laradi Sandrine (Author), Miled Abdelhedi (Author)
• Format: Book
• Published: BMC, 2011-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is X-linked recessive lysosomal storage disorder resulting from the defective activity of the enzyme iduronate-2-sulfatase (IDS). Hunter disease can vary from mild to severe, depending on the level of enzyme...