Reliable computational quantification of liver fibrosis is compromised by inherent staining variation

• Main Authors: Stuart Astbury (Author), Jane I Grove (Author), David A Dorward (Author), Indra N Guha (Author), Jonathan A Fallowfield (Author), Timothy J Kendall (Author)
• Format: Book
• Published: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Biopsy remains the gold‐standard measure for staging liver disease, both to inform prognosis and to assess the response to a given treatment. Semiquantitative scores such as the Ishak fibrosis score are used for evaluation. These scores are utilised in clinical trials, with the US Food and...