Oleuropein enhances proteasomal activity and reduces mutant huntingtin-induced cytotoxicity

IntroductionHuntington's disease (HD) is a hereditary neurodegenerative disorder that primarily affects the striatum, a brain region responsible for movement control. The disease is characterized by the mutant huntingtin (mHtt) proteins with an extended polyQ stretch, which are prone to aggrega...

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Main Authors: Zih-Ning Huang (Author), Sin-Yi Lee (Author), Jie-Mao Chen (Author), Zih-Ting Huang (Author), Lu-Shiun Her (Author)
Format: Book
Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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