PGE2 Promotes the Migration of Mesenchymal Stem Cells through the Activation of FAK and ERK1/2 Pathway

• Main Authors: Xiaomin Lu (Author), Jibin Han (Author), Xiuping Xu (Author), Jingyuan Xu (Author), Ling Liu (Author), Yingzi Huang (Author), Yi Yang (Author), Haibo Qiu (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A critical step of MSCs therapy is dependent on its ability to migrate into the sites of injury, so various approaches have been introduced to boost the migratory ability of MSCs. PGE2 is the major prostaglandin generated by COX enzymes and has been implicated in inflammatory response. Evidence indi...