Synthesis and evaluation of platinum complexes with potential antitumor activity

• Prif Awduron: Rachel Lima Marcelino Freire (Awdur), Maria Betânia de Freitas Marques (Awdur), Elaine Maria de Souza-Fagundes (Awdur), Renata Barbosa de Oliveira (Awdur), Ricardo José Alves (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Universidade de São Paulo, 2017-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract A novel series of platinum (II) complexes was synthesized and the complexes were evaluated for their in vitro cytotoxicity against four human cancer cells lines. Five platinum complexes showed activity against at least one tumor cell line. Complexes 3 and 6 were promising, being active, at...