Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel

Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel

P2X7, an ion channel gated by extracellular ATP, is widely expressed on the plasma membrane of immune cells and plays important roles in inflammation and apoptosis. Several single nucleotide polymorphisms have been identified in the human P2RX7 gene. In contrast to other members of the P2X family, n...

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Main Authors: Waldemar Schäfer (Author), Tobias Stähler (Author), Carolina Pinto Espinoza (Author), Welbeck Danquah (Author), Jan Hendrik Knop (Author), Björn Rissiek (Author), Friedrich Haag (Author), Friedrich Koch-Nolte (Author)
Format: Book
Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
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