Lipidomic Analyses Uncover Apoptotic and Inhibitory Effects of Pyrvinium Pamoate on Cholangiocarcinoma Cells via Mitochondrial Membrane Potential Dysfunction

• Κύριοι συγγραφείς: Yingpinyapat Kittirat (Συγγραφέας), Jutarop Phetcharaburanin (Συγγραφέας), Bundit Promraksa (Συγγραφέας), Thanaporn Kulthawatsiri (Συγγραφέας), Arporn Wangwiwatsin (Συγγραφέας), Poramate Klanrit (Συγγραφέας), Sakkarn Sangkhamanon (Συγγραφέας), Apiwat Jarearnrat (Συγγραφέας), Suyanee Thongchot (Συγγραφέας), Panupong Mahalapbutr (Συγγραφέας), Watcharin Loilome (Συγγραφέας), Hideyuki Saya (Συγγραφέας), Nisana Namwat (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Pyrvinium pamoate (PP), an FDA-approved anthelmintic drug, has been validated as a highly potent anti-cancer agent and patented recently as a potential chemotherapeutic drug for various cancers. The aims of this study were, therefore, to investigate the ability of PP in anti-proliferative activity a...