The Nimodipine-Sparing Effect of Perioperative Dexmedetomidine Infusion During Aneurysmal Subarachnoid Hemorrhage: A Prospective, Randomized, Controlled Trial

• Main Authors: Chunguang Ren (Author), Jian Gao (Author), Guang jun Xu (Author), Huiying Xu (Author), Guoying Liu (Author), Lei Liu (Author), Liyong Zhang (Author), Jun-Li Cao (Author), Zongwang Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Nimodipine can block the influx of calcium into the vascular smooth muscle cell and prevent secondary ischemia in patients with aneurysmal subarachnoid hemorrhage. However, the reduction of blood pressure after long-term intravenous administration of nimodipine has been associated with n...