Activation of Cytosolic Phospholipase A2α by Epidermal Growth Factor (EGF) and Phorbol Ester in HeLa Cells: Different Effects of Inhibitors for EGF Receptor, Protein Kinase C, Src, and C-Raf

• Glavni autori: Yasuo Matsuzawa (Autor), Yoshiaki Kiuchi (Autor), Kaori Toyomura (Autor), Ikiru Matsumoto (Autor), Hiroyuki Nakamura (Autor), Hiromichi Fujino (Autor), Toshihiko Murayama (Autor), Tatsuo Kawashima (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2009-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

In several types of cancer cells, prostaglandins produced via the over-expression of epidermal growth factor receptor (EGFR) and cyclooxygenases regulate cell growth. We investigated the signaling mechanisms for the release of arachidonic acid (AA, a precursor for prostaglandins) in human cervical c...