Utilizing induced neural stem cell‐based delivery of a cytokine cocktail to enhance chimeric antigen receptor‐modified T‐cell therapy for brain cancer

• Asıl Yazarlar: Alex S. Woodell (Yazar), Elisa Landoni (Yazar), Alain Valdivia (Yazar), Andrew Buckley (Yazar), Edikan A. Ogunnaike (Yazar), Gianpietro Dotti (Yazar), Shawn D. Hingtgen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2023-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Chimeric antigen receptor (CAR)‐modified T‐cell therapy has shown enormous clinical promise against blood cancers, yet efficacy against solid tumors remains a challenge. Here, we investigated the potential of a new combination cell therapy, where tumor‐homing induced neural stem cells (iNSC...