Characterization of Pathway-Specific Regulator NigR for High Yield Production of Nigericin in <i>Streptomyces malaysiensis</i> F913
Nigericin is a polyether antibiotic with potent antibacterial, antifungal, antimalarial and anticancer activity. NigR, the only regulator in the nigericin biosynthetic gene cluster in <i>Streptomyces malaysiensis</i> F913, was identified as a SARP family regulator. Disruption of <i>...
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MDPI AG,
2022-07-01T00:00:00Z.
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