Suppressive Effects of GSS on Lipopolysaccharide-Induced Endothelial Cell Injury and ALI via TNF-α and IL-6

• Main Authors: Lei Yi (Author), Zengding Zhou (Author), Yijuan Zheng (Author), Mengling Chang (Author), Xiaoqin Huang (Author), Feng Guo (Author), Quanming Zhao (Author), Jingning Huan (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Under septic conditions, LPS induced lung vascular endothelial cell (EC) injury, and the release of inflammatory mediator launches and aggravates acute lung injury (ALI). There are no effective therapeutic options for ALI. Genistein-3'-sodium sulfonate (GSS) is a derivative of nativ...