DNA methylation differences in monozygotic twins with Van der Woude syndrome

• Päätekijät: A. L. Petrin (Tekijä), E. Zeng (Tekijä), M. A. Thomas (Tekijä), D. Moretti-Ferreira (Tekijä), M. L. Marazita (Tekijä), X. J. Xie (Tekijä), J. C. Murray (Tekijä), L. M. Moreno-Uribe (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

IntroductionVan der Woude syndrome (VWS) is an autosomal dominant disorder responsible for 2% of all syndromic orofacial clefts (OFCs), with IRF6 being the primary causal gene (70%). Cases may present with lip pits and either cleft lip, cleft lip with cleft palate, or cleft palate, with marked pheno...