Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation

Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation

Chronic, systemic inflammation is a pathophysiological manifestation of metabolic disorders. Inflammatory signaling leads to elevated glycolytic flux and a metabolic shift towards aerobic glycolysis and lactate generation. This rise in lactate corresponds with increased generation of lactoylLys modi...

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Main Authors: Marissa N. Trujillo (Author), Erin Q. Jennings (Author), Emely A. Hoffman (Author), Hao Zhang (Author), Aiden M. Phoebe (Author), Grace E. Mastin (Author), Naoya Kitamura (Author), Julie A. Reisz (Author), Emily Megill (Author), Daniel Kantner (Author), Mariola M. Marcinkiewicz (Author), Shannon M. Twardy (Author), Felicidad Lebario (Author), Eli Chapman (Author), Rebecca L. McCullough (Author), Angelo D'Alessandro (Author), Nathaniel W. Snyder (Author), Darren A. Cusanovich (Author), James J. Galligan (Author)
Format: Book
Published: Elsevier, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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