Intranasal delivery of Salmonella OMVs decorated with Chlamydia trachomatis antigens induces specific local and systemic immune responses

• Main Authors: Dung T. Huynh (Author), Emanuele Nolfi (Author), Lobna Medfai (Author), Peter van Ulsen (Author), Wouter S. P. Jong (Author), Alice J. A. M. Sijts (Author), Joen Luirink (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Fag: article
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ABSTRACTChlamydia trachomatis is an obligate intracellular pathogen responsible for the most prevalent bacterial sexually transmitted disease globally. The high prevalence of chlamydial infections underscores the urgent need for licensed and effective vaccines to prevent transmission in populations....