Secretion of One Adipokine Nampt/Visfatin Suppresses the Inflammatory Stress-Induced NF-κB Activity and Affects Nampt-Dependent Cell Viability in Huh-7 Cells

• Главные авторы: Yi-Ching Lin (Автор), Hui-Chung Wu (Автор), Chen-Chung Liao (Автор), Yi-Chih Chou (Автор), Shwu-Fen Pan (Автор), Chi-Ming Chiu (Автор)
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• Опубликовано: Hindawi Limited, 2015-01-01T00:00:00Z.
• Предметы: article
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Nampt/visfatin acts in both intracellular and extracellular compartments to regulate multiple biological roles, including NAD metabolism, cancer, inflammation, and senescence. However, its function in chronic inflammation and carcinogenesis in hepatocellular carcinoma (HCC) has not been well-defined...