FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease

• Autors principals: Ho-Chang Kuo (Autor), Yu-Wen Hsu (Autor), Mei-Shin Wu (Autor), Peng Yeong Woon (Autor), Henry Sung-Ching Wong (Autor), Li-Jen Tsai (Autor), Ruo-Kai Lin (Autor), Sukhontip Klahan (Autor), Kai-Sheng Hsieh (Autor), Wei-Chiao Chang (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2015-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Kawasaki disease (KD) is characterized by pediatric systemic vasculitis of an unknown cause. The low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) gene was reported to be involved in the susceptibility of KD. DNA methylation is one of the epigenetic mechanisms that control gene expr...