FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease

• Main Authors: Ho-Chang Kuo (Author), Yu-Wen Hsu (Author), Mei-Shin Wu (Author), Peng Yeong Woon (Author), Henry Sung-Ching Wong (Author), Li-Jen Tsai (Author), Ruo-Kai Lin (Author), Sukhontip Klahan (Author), Kai-Sheng Hsieh (Author), Wei-Chiao Chang (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Kawasaki disease (KD) is characterized by pediatric systemic vasculitis of an unknown cause. The low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) gene was reported to be involved in the susceptibility of KD. DNA methylation is one of the epigenetic mechanisms that control gene expr...