Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis

• Main Authors: Gamal Shiha (Author), Ahmed Nabil (Author), Ahmed Lotfy (Author), Reham Soliman (Author), Ayman A. Hassan (Author), Islam S. Ali (Author), Doaa F. Gad (Author), Faten Zahran (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis is the excessive extracellular matrix accumulation of proteins, such as collagen, which follows the chronic liver diseases. Advanced liver fibrosis leads to cirrhosis and liver failure. Nilotinib is a second-generation tyrosine kinase inhibitor, which showed antifibrotic efficacy. Ste...