Novel Purine Chemotypes with Activity against <i>Plasmodium falciparum</i> and <i>Trypanosoma cruzi</i>

• Main Authors: Nieves Martinez-Peinado (Author), Álvaro Lorente-Macías (Author), Alejandro García-Salguero (Author), Nuria Cortes-Serra (Author), Ángel Fenollar-Collado (Author), Albert Ros-Lucas (Author), Joaquim Gascon (Author), Maria-Jesus Pinazo (Author), Ignacio J. Molina (Author), Asier Unciti-Broceta (Author), Juan J. Díaz-Mochón (Author), María J. Pineda de las Infantas y Villatoro (Author), Luis Izquierdo (Author), Julio Alonso-Padilla (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malaria and Chagas disease, caused by <i>Plasmodium</i> spp. and <i>Trypanosoma cruzi</i> parasites, remain important global health problems. Available treatments for those diseases present several limitations, such as lack of efficacy, toxic side effects, and drug resistance...