Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

Failure to recognize important features of a drug's pharmacokinetic characteristics is a key cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and increased rate of adverse drug reactions requiring medical intervention. As oral chemotherapeutic agents, tyrosin...

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Main Authors: Dominique A. Garrison (Author), Zahra Talebi (Author), Eric D. Eisenmann (Author), Alex Sparreboom (Author), Sharyn D. Baker (Author)
Format: Knjiga
Izdano: MDPI AG, 2020-09-01T00:00:00Z.
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