Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors

• मुख्य लेखकों: Dominique A. Garrison (लेखक), Zahra Talebi (लेखक), Eric D. Eisenmann (लेखक), Alex Sparreboom (लेखक), Sharyn D. Baker (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Failure to recognize important features of a drug's pharmacokinetic characteristics is a key cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and increased rate of adverse drug reactions requiring medical intervention. As oral chemotherapeutic agents, tyrosin...