Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol

• Main Authors: Shinobu Shimizu (Author), Shuhei Tsuchiya (Author), Akihiro Hirakawa (Author), Katsuyoshi Kato (Author), Masahiko Ando (Author), Masaaki Mizuno (Author), Masashi Osugi (Author), Kazuto Okabe (Author), Wataru Katagiri (Author), Hideharu Hibi (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Maxillomandibular bone defects arise from maxillofacial injury or tumor/cyst removal. While the standard therapy for bone regeneration is transplantation with autologous bone or artificial bone, these therapies are still unsatisfactory. Autologous bone harvesting is invasive and...