Pathogenicity of Treponema denticola Wild-Type and Mutant Strain Tested by an Active Mode of Periodontal Infection Using Microinjection

• Hoofdauteurs: Jacques Izard (Auteur), Hajime Sasaki (Auteur), Ralph Kent (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2012-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The available passive mode of periodontal infections in mice requires high efficiency of bacterial attachment and invasiveness and is not always suitable to test the pathogenicity of genetically engineered mutant strains. We developed an active mode of oral infection, using microinjection in the mar...