Association of genetic variants related to combined exposure to higher BMI and waist-to-hip ratio on lifelong cardiovascular risk in UK Biobank

• Main Authors: Eric Yuk Fai Wan (Author), Wing Tung Fung (Author), Esther Yee Tak Yu (Author), Will Ho Gi Cheng (Author), Kam Suen Chan (Author), Yuan Wang (Author), Esther Wai Yin Chan (Author), Ian Chi Kei Wong (Author), Cindy Lo Kuen Lam (Author)
• Format: Book
• Published: Cambridge University Press, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective: This study examines the individual and combined association of BMI and waist-to-hip ratio (WHR) with CVD risk using genetic scores of the obesity measurements as proxies. Design: A 2 × 2 factorial analysis approach was applied, with participants divided into four groups of lifeti...