Luteolin Enhances Choroid Plexus 5-MTHF Brain Transport to Promote Hippocampal Neurogenesis in LOD Rats

• Main Authors: Hui-Zhen Li (Author), Kai-Ge Liu (Author), Ning-Xi Zeng (Author), Xiao-Feng Wu (Author), Wen-Jun Lu (Author), Han-Fang Xu (Author), Can Yan (Author), Li-Li Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Folates, provided by food, are commonly used antidepressant synergists in late-onset depression (LOD). However, increased intake of folic acid in the elderly population might lead to the accumulation of unmetabolized folic acid in the systemic circulation, leading to enhanced deterioration of the ce...